How specific is too specific? B‐cell responses to viral infections reveal the importance of breadth over depth

How specific is too specific? B‐cell responses to viral infections reveal the importance of breadth over depth

Source :

• Immunological Reviews [ 0105-2896 ] ; 2013-09.

English descriptors

• Teeft :
  • Acad, Antibodies bind, Antibody, Antibody production, Antibody repertoire, Antibody response, Antibody responses, Antigenic, Antiviral, Antiviral antibody responses, Antiviral response, Autoantibody, Autoimmune disease, Baumgarth, Baumgarth responses, Body cavities, Body cavity cells, Bone marrow, Bronchoalveolar lavage, Cell development, Cell migration, Cell population, Cell redistribution, Cell response, Challenge infection, Clonal expansion, Clone, Drive extrafollicular responses, Earliest antibodies, Early studies, Epitope, Extrafollicular, Extrafollicular foci, Extrafollicular foci response, Extrafollicular response, Extrafollicular responses, Further studies, Gene expression, Germinal, Germinal center, Germinal center reaction, Germinal center reactions, Germinal center response, Germinal center responses, Germinal centers, Herzenberg, Heterosubtypic immunity, Homotypic virus, Humoral, Humoral immunity, Immune, Immune defense, Immune protection, Immune response, Immune responses, Immune system, Immunoglobulin, Immunol, Immunological, Immunological reviews, Immunological reviews baumgarth responses, Infection, Infectious virus, Initial studies, John wiley sons, Lymph, Lymph nodes, Lymphoid, Many months, Mouse, Mucosal surfaces, Mutation, Natl, Natural antibodies, Natural antibody repertoire, Natural cells, Neutralizing, Neutralizing antibodies, Node, Normal development, Other signals, Pandemic, Pandemic strain, Pathogen, Peritoneal, Peritoneal cavity, Plasma cells, Polyreactive, Polyreactive antibodies, Polyreactivity, Primary infection, Primary response, Primary virus infection, Proc, Proc natl acad, Protective antibodies, Recent studies, Receptor, Regional lymph nodes, Reinfection, Repertoire, Respiratory tract, Secondary lymphoid tissues, Secondary response, Selection model, Serum antibodies, Small subset, Somatic hypermutation, Somatic hypermutations, Somatic mutation, Spleen, Spontaneous cells, Subset, Unpublished data, Vaccine, Viral, Viral infections, Virus, Virus hemagglutinin, Virus infection, Virus neutralization, Virus strains, Wiley.

Abstract

• https://api.istex.fr/ark:/67375/WNG-DKJ84GCM-R/fulltext.pdf

Affiliations:

• États-Unis

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